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POPs disrupt cardiovascular homeostasis by interfering with estrogen signaling, impairing blood pressure regulation, and inducing oxidative stress-mediated inflammation [52]

In agreement with these reports, Doxorubicin induced senescence in IMR90 in vitro , evident by elevated SA--GAL activity, expression of p16 ink4a , and the early and late SASP factors IL-1 and IL-6 (Orjalo et al., 2009), respectively (Fig

NASH often progresses silently and may be related to dietary imbalances , sedentary lifestyle, overweight, or certain predispositions

It also reduces liver TC and TG levels [87]

The oxidative potential of airborne particulate matter research trends, challenges, and future PerspectivesInsights from a bibliometric analysis and scoping review