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Neuroendocrine control of sleep

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In this line, GSH depletion in glial cells, including astrocytes, leads to neuroinflammatory phenotype ( 2+ -dependent glutamate release from microglial cells is observed upon hypoxia-mediated redox imbalance likely via the activation of IP 3 R which could participate in excitotoxic damages during brain insults ( 2+ homeostasis and thus result in unregulated Ca 2+ -dependent release of factors as proinflammatory cytokines or glutamate endangering neuronal cell survival

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What the Evidence Actually Shows Being honest about evidence is part of good medical content

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USA 111 , E4568E4576 (2014)

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