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Another study showed that the relative abundance of Firmicutes and the portion of Ruminococcaceae decreased, while Bacteroidetes increased when followed simvastatin therapy (114)

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doi: 10.3389/fmicb.2024.1354823 70 BennettBJde Aguiar VallimTQWangZShihDMMengYGregoryJet al

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Further, AR45 protein interacts with membrane-associated G proteins Gq and Go