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doi: 10.1007/s13311-022-01308-6 272 SperlingR

BBR lowered pro-inflammatory cytokines (IL-1, IL-6, TNF-), mitigated HFD-induced metabolic endotoxemia, and improved obesity-related metabolic dysfunctions [36]

As an alkaloid, SIN readily forms water-soluble salts upon reaction with acids, while its lipophilic nature facilitates gastrointestinal absorption through passive diffusion

Clinical research has consistently demonstrated that supplementation with folic acid, vitamin B, and vitamin B can effectively lower homocysteine concentrations

doi: 10.1016/j.arcmed.2020.04.019 58 DenekeS

Treatments targeting these age-related alterations are considered as potential approaches to prevent pathogenic deterioration and frailty (14)
