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Conflicts of Interest The authors declare that there is no conflict of interest regarding the publication of this paper

J Public Health

[6] Concomitant use with oral anticoagulants such as warfarin may enhance anticoagulation and alter international normalised ratio values, so prothrombin time should be reviewed more frequently following dose changes of either drug

Turning the growth hormone receptor on: evidence that hormone binding induces subunit rotation

Inflamed intestinal tissues show upregulated -arrestins (-arrs), triggering ER stress [66]

This conclusion is further supported by the observation that mice lacking Epac1 , which encodes one of the two isoforms of EPAC in mammals, are more resistant to DIO and have improved glucose tolerance and heightened central leptin sensitivity, as measured through STAT3 activation, compared with control mice 98