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Description
Existing and potential therapeutic uses for n-acetylcysteine: the need for conversion to intracellular glutathione for antioxidant benefits

[PUBMED Abstract] Childhood cancer

Francis AM, Sepesi B, Correa AM, Blum MA, Erasmus JJ, Lee JH, Maru DM, Mehran RJ, Rice DC , Roth JA, Vaporciyan AA, Walsh GL, Welsh JW, Swisher SG, Hofstetter WL, Cancer Group UOTMAE

Timing: Some medications are administered daily, while others may require weekly injections

This is where the glutathione versus NAC debate becomes particularly important

149 An alternative means of linking a bile acid to a platinum(II) center involves conjugation to the nonleaving group ligands, a strategy that has afforded complexes demonstrating activity in cultured cells via a mechanism of action similar to that of cisplatin
