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Novel genomic targets in oxidant-induced vascular injury

Handb Exp Pharmacol (2022) 270:40525

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Structural and functional characterization of Nrf2 degradation by the glycogen synthase kinase 3/( -TrCP axis

Moreover, it should be noted that the accumulation of fructose has been suggested to be more deleterious than that of glucose [75, 81] as fructose metabolism by fructokinase bypasses key-regulated steps of the glycolytic pathway [82] and thus can deplete intracellular phosphate and ATP, thereby inducing oxidative stress and inflammation [83]

Kurzweil remains undeterred