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Acknowledgements The authors thank all investigators and staff involved in the conduct of this clinical trial

Data sources Incidence and prevalence of IBD were calculated for Canada, Denmark and Scotland (Lothian) from administrative data provided by each region (Supplementary Table 7)

Most clients experience minimal side effects, such as mild soreness, redness, or bruising at the injection site

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Open dialogue is essential to ensuring patient safety in an environment where access to unregulated compounds is increasingly common

Tumor vasculature shares some similarities with adipose vasculature