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Description
They start with high doses to fill up their vitamin B12 stores
4, e919 (2013)
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The 2024 Yang paper in Journal for ImmunoTherapy of Cancer documented NNMT in cancer-associated fibroblasts driving tumour progression (PMID 39067875)
and the same clinical dose of the TNF- antibody used in rheumatoid arthritis has a definite effect on bronchial asthma, but has not been confirmed in COPD
It is also more common in older adults, as the bodys ability to absorb vitamin B12 from food decreases with age
