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Description
Glycerol phenylbutyrate (GPB) is a medication approved by the Food and Drug Administration in 2013 for the treatment of patients with urea cycle disorders or innate metabolism errors that manifest as hyperammonemia, whose effect was emulated in the cirrhotic population.49 GPB is hydrolyzed by pancreatic lipases for producing glycerol and 3 molecules of phenylbutyric acid
PAL-Se NPs up-regulated the ROS level and induced apoptosis in U87 glioma cells, which was demonstrated by in vitro and in vivo analysis

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