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In an in vivo study on full-thickness wounds in mice, it demonstrated wound-healing activity by inducing secretion of TNF and TGF-1 and by scavenging free radicals [246]

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4.3.2.9 Summary and conclusions The working group convened by IARC in 1998 (IARC 1999) concluded that there was sufficient evidence in humans for the carcinogenicity of combined oral contraceptives