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Mitochondrial glutathione: Hepatocellular survival-death switch

The potential for causing permanent damage, inflammation (uveitis), glaucoma, or other serious eye conditions is a real risk that far outweighs any cosmetic desire

K., Hemshekhar, M., Kemparaju, K

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It can prevent damage to important cellular components caused by reactive oxygen species such as free radicals or peroxides

GS is responsible for triggering the reaction that synthesizes glutamine from ammonium ion (NH 4+ ), and glutamate through ATP consumption, whereas GLS is responsible for glutamine hydrolysis, which converts it into glutamate and NH 4+ again [22,23] (Figure 1)