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however, people with DAMD exhibit higher levels of serum iron, retinal iron, and ferritin, an iron-sequestering protein, compared to healthy controls, implying disrupted iron homeostasis [191,192,193]

Oncotarget 8(10):17216

However, for many, there is an underlying cause (or causes) that increases the risk of developing mast cell activation syndrome

10.1186/s13048-017-0342-3 J Ovarian Res

rather, it translates microbial metabolic cues into a spectrum of cellular responses that collectively sculpt the immunological landscape of the tumor, influencing cellular composition, functional orientation, and the balance between anti-tumor immunity and immune evasion

However, several limitations should be acknowledged: (i) the limited sample size reduces the generalizability of the findings and prevents establishing causal links regarding sex or mutation-specific metabolic alterations