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The role of the gut barrier function in health and disease

Thus, we identified a cell death checkpoint that depends on the non-metabolic function of HK2 in TNF-induced RIPK1-mediated cell death, revealing a potential therapeutic avenue for RIPK1-related diseases through HK2 non-metabolic functions

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Paris saponins I, II, and VII similarly reduce fluorescence intensity and activate apoptosis through p53 and Wnt signaling (Ni et al., 2023), while sesquiterpenes like -eudesmol impair hepatic function through metabolic interference (Tshering et al., 2022)

RH: Investigation, Writing review & editing, Methodology, Formal analysis

Engrailed-2 is another transcription factor that influences several biological processes implicated in ASD, as Engrailed-2 is located in the ASD-susceptibility region on the human chromosome [165,166,167]
