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However, humans have far fewer GLP-1 receptors in thyroid C-cells than rodents

Nutrients 2021;13:3530

The peptide functions by stimulating lipolysisthe breakdown of fatsand inhibiting lipogenesis, the formation of new fat

Endocrine disorders:inappropriate ADH syndrome Eye disorders:diplopia Gastrointestinal disorders:increased salivation, nausea/vomiting General disorders and administration site conditions:chills, edema, unexplained death, weakness Hepatobiliary disorders:cholestasis, jaundice, hyperbilirubinemia, liver enzyme alterations Investigations:increased amylase Metabolism and nutrition disorders:methemoglobinemia Nervous system disorders:aphasia, ataxia, cerebrovascular accident, extrapyramidal symptoms, grand mal seizures, paresthesia, tardive dyskinesia, vertigo Psychiatric disorders:abnormal dreams, agitation, anxiety, hallucinations, insomnia, paranoid reaction, psychosis, stupor Renal and urinary disorders:urinary incontinence, urinary retention Reproductive system and breast disorders:breast enlargement or engorgement, clitorism, lactation, priapism [see Warnings and Precautions ( 5.6)] Respiratory, thoracic and mediastinal disorders:apnea Skin and subcutaneous tissue disorders:alopecia, hirsutism, leukonychia, pruritus, psoriasis, rash, urticaria Vascular disorders:vasodilation Pregnancy Exposure Registry There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to antidepressants during pregnancy

[101] Nanotechnologies used in vitamin B 12 supplementation Conventional administration does not ensure specific distribution and controlled release of vitamin B 12 , for example to bone marrow and nerve cells

Some genetic diseases that involve defects of transcobalamin, methylmalonyl CoA mutase, or enzymes in the pathway of cobalamin adenosylation, may also result in vitamin B12 deficiency (IOM, 2000)