how does glutathione-s-transferase cause drug resistance in cancer cells Role of Glutathione Cancer: From Mechanisms to Therapies The Relationship of Glutathione-S-Transferase and

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In gliomas of varying degrees, Zeng et al

As such, the prodrug approach will remain an important strategy in future drug discovery, contributing to the design of safer and more effective treatments for complex diseases and individual patient needs

this has contributed to acquiring a better physiological understanding of their metabolism in humans, while also highlighting the challenges and limitations of the current trials

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Interestingly, in comparison of APAP and APAP-CYS at 1 mM, the latter was capable to increase the GCLC protein expression approximately one-fold