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Nrf2 can in turn regulate S1R gene expression, and in sorafenib-treated HCC cells, if Nrf2 is inactivated and intracellular ROS accumulation, S1R expression is upregulated to protect HCC cells from ferroptosis [151]

Oxidative Stress and Lipid Peroxidation Products in Cancer Progression and Therapy

Front Pharmacol (Internet) 6, 286.CrossRefGoogle ScholarPubMed Zhai, Z, Fu, Y, Zhang, X, et al

Ihnatowicz P, Drywie M, Wtor P, Wojsiat J (2020) The importance of nutritional factors and dietary management of Hashimotos thyroiditis

Taken together, these data indicate that H-GSH rats have a longer active engagement in the PR test than L-GSH rats and, their superior performance is not due to a higher rate of responses at the beginning of the PR test

Additionally, strategies to mitigate mitochondrial damage, protect endothelial cells, promote angiogenesis, and modulate anti-inflammatory responses and apoptosis are also important for alleviating LL-IRI
