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Low holotranscobalamin II or elevated MMA levels despite taking vitamin B12 supplements consistently is an indication youll need to discuss an alternative plan of action with your physician or plant-based dietitian

When B12 runs low, symptoms tend to creep in slowly enough to get blamed on something else: persistent fatigue, brain fog, low mood, weight gain or difficulty losing weight, weakness, tingling in the hands or feet, shortness of breath, and a weakened immune system

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Methylmalonic acid in serum from patients with neurological symptoms consistent with cobalamin deficiency

These issues are often the primary reason people need a consistent, long-term injection schedule

Doses are tailored