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5-amino-1MQ stimulates the growth of nicotinamide adenine dinucleotide (NAD +), a cofactor that is crucial for cellular metabolism, thereby increasing the metabolic rate and activating a gene called sirtuin-1 (SIRT1)

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Vitamin B12 deficiency results in megaloblastic anemia, GI lesions, and neurologic damage (which begins with an inability to produce myelin and is followed by gradual degeneration of the axon and nerve head)

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