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Retrieved 6 January 2022, from Adunsky A, Chandler J, Heyden N, Lutkiewicz J, Scott BB, Berd Y, Liu N, Papanicolaou DA
Lysates were centrifuged at 15,000 g for 10 min at 4 C
Increased expression of c-Met is associated with chemotherapy-resistant breast cancer and poor clinical outcome
Cells 12 , 21 (2022)
To further mitigate risk, many studies involve sentinel subjects typically only 1 participant on the active drug and 1 on placebo who receives the investigational drug before the remaining participants in the cohort are dosed
The temporal association with starting B12 supplementation may simply reflect chance occurrence rather than causation
