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125,139 Under chronic hyperglycemia, glycolysis becomes saturated, and excessive ROS are produced by alternative metabolic pathways to induce oxidative stress, causing mitochondrial and DNA damage

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The ability of probiotics to adhere to epithelial cells is a desirable characteristic of beneficial microorganisms allowing them to manifest their beneficial effects by persisting longer in the host GI tract (Collado et al., 2008

Trials so far are small and sometimes inconclusive, and the ideal dose, schedule, and stacking approach remain open questions

This redox cycling provides continuous protection against oxidative damage to proteins, lipids, and DNA