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[2] As a nutraceutical ingredient, AOD-9604 has been evaluated under Generally Recognized as Safe (GRAS) frameworks, and its pharmacological profile continues to inform mechanistic studies examining the intersection of lipid metabolism, adipose tissue biology, and peptide pharmacology
In this reaction, selenite reacts with glutathione (GSH), forming GS-Se-SG, which is then reduced by NADPH and GSH reductase to the unstable intermediate GS-Se
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A deficiency of GSH puts the cell at risk for oxidative damage
