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Biocatalytic and antioxidant nanostructures for ROS scavenging and biotherapeutics

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The skin has the advantage of being an easy and convenient route of administration for a wide range of active ingredients, including natural or synthetic cannabinoids

Separately, there is an extensive intestinal metabolism, including phase II enzymatic reactions (glucuronidation, sulfation, methylation), which are additionally observed in the subsequent hepatic biotransformation

Cullin3-cased polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling