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In NSCLC, Alimta is approved for various settings, including initial treatment in combination with cisplatin for locally advanced or metastatic non-squamous NSCLC, as maintenance therapy after initial chemotherapy, and as a single agent for patients with locally advanced or metastatic non-squamous NSCLC after prior chemotherapy

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Pharmacological inhibition of CBP/p300 blocks estrogen receptor alpha (ER) function through suppressing enhancer H3K27 acetylation in luminal breast cancer

Dehydration: Lack of adequate hydration can disrupt the balance of electrolytes, which are essential for muscle function

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The investigators reported that all cultures were observed to develop different degrees resistance to UVC inactivation after 80 consecutive cycles of sub-lethal bacterial inactivation and regrowth
