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Depuydt et al., 2009)

Human cells that express ACE2 are potential targets for SARS-CoV-2 infection

Additionally, in another Phase II study targeting patients with T2DM, orforglipron also showed significant effects in reducing A1C and weight, achieving the studys primary and secondary endpoints

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doi: 10.1210/en.2014-1110 135 KowLMFloreaCSchwanzel-FukudaMDevidzeNKami KiaHLeeAet al

Category 2 means the FDA has determined that the substance "may present significant safety risks" when used in compounding
