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A prior study demonstrated that NLRP3 inflammasome activation induced the generation of mtROS, which directed the binding of GSDMD to the mitochondrial membrane, thus forming mitochondrial GSDMD pores and then causing the release of mtROS (82)

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5-Chac1 (K0)-Myc) where all lysine residues were replaced with arginines because the mouse Chac1 protein has five lysine residues in the coding region (Fig

[DOI] [PubMed] [Google Scholar] 6.Hayes J.D., Flanagan J.U., Jowsey I.R

[DOI] [PubMed] [Google Scholar] 30.Sikiric P, Seiwerth S, Brcic L, Blagaic AB, Zoricic I, Sever M, et al

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