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Plant domestication decreases both constitutive and induced chemical defences by direct selection against defensive traits

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460,461 On the one hand, in relation to normal cells which lactate/lactylation exerts a pivotal effect on its physiological functions, lactate/lactylation targeted therapy may inflict a fatal blow to their structure and operation

[DOI] [PMC free article] [PubMed] [Google Scholar] 95.Persoons E., Hennes A., De Clercq K., Van Bree R., Vriens G., O D.F., Peterse D., Vanhie A., Meuleman C., Voets T., et al

Extracellular matrices and cancer-associated fibroblasts: Targets for cancer diagnosis and therapy