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Description
The most important THRs for mediating the actions of thyroid hormones are [13, 15, 16]: THR1: expressed most strongly in bone, the gut, the central nervous system, and cardiac and skeletal muscle THR1: expressed most strongly in the liver, kidney, and the inner ear THR2: expressed most strongly in the hypothalamus, pituitary, cochlea, and retina THR2 appears to be about ten-fold more sensitive than THR1 [13]

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Lithium increases tyrosine hydroxylase levels both in vivo and in vitro

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