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Alzheimers Dement (N Y) 7(1):e12160 2021 PMC8033410 Hayden KM, Neiberg RH, Evans JK, Luchsinger JA, Carmichael O, Dutton GR, Johnson KC, Kahn SE, Rapp SR, Yasar S, Espeland MA, Action for Health in Diabetes Research Group

Sleep and Diet: Mounting Evidence of a Cyclical Relationship

In combination these will reduce mental fatigue and improve productivity
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Inhibition of pyruvate dehydrogenase kinase 2 protects against hepatic steatosis through modulation of tricarboxylic acid cycle anaplerosis and ketogenesis

Studies indicate this supramolecular formulation may suppress pro-inflammatory cytokines (TNF-, IL-8, PGE-2) and reduce melanin levels in vitro, with clinical validation suggesting 3% essence concentrations supported significant skin brightening effects in human subjects
