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10.1039/c7sc05476a 25 YinJ.LaoF.FuP.WamerW.ZhaoY.WangP.et al (2009)
doi: 10.1038/s41598-017-14889-6
Nutrients 11 , (2019)

Overall, the Keto-CARE trial demonstrates that sustained nutritional ketosis is feasible during treatment, yielding a 16% fasting glucose reduction and a 67% decrease in insulin resistance without compromising safety
doi: 10.1007/s00280-008-0924-2
It also may help reduce the risk of cardiovascular diseases, diabetes, and certain cancers (breast, renal, and colon).39 Citrus bioflavonoids show promise in protecting against oxidative stress, inflammation, diabetes, atherosclerosis, and other conditions.40 And artichoke leaf extract may be able to protect the liver, promote bile secretion, lower cholesterol, and potentially even help liver cells regenerate, though more research is needed.41 Only Nested Naturals contains a similar ingredient in the form of Jerusalem artichoke inulin powder