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Ultimately, advancements in these areas will determine whether probiotics and related live biotherapeutics can transition from broadly categorized health-promoting supplements to precisely targeted, mechanism-based interventions that are incorporated into evidence-based guidelines for both prevention and treatment (294)

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Ethical approval was obtained from the Regulations of the Animal Experimentation Committee, Biological Science Center, KAC Co., Ltd

10.3390/cells10051236 31 CarlsonC