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Furthermore, the resonance energy transfer from tyrosine to tryptophan was very inefficient (Jones and Rumsby, 1975), suggesting that MBP is characterized by extended conformation

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doi: 10.3389/fendo.2025.1573526 Received 09 February 2025 Accepted 15 September 2025 Published 01 October 2025 Volume 16 - 2025 Edited by Claus Yding Andersen, University of Copenhagen, Denmark Reviewed by Gennaro Lettieri, University of Naples Federico II, Italy Anitha Myla, Mississippi State Department of Health, United States Updates Copyright 2025 Han and Jin

Use gentle, low-pressure language: Try You dont have to do this alone, or Would you be open to talking to someone? Offer clear options, not ultimatums: Therapy can provide emotional support, psychiatry can help with medication guidance (including mood stabilizers, when clinically appropriate), and structured clinical care may help when symptoms affect daily life