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TAAR1 activation initiates signaling cascades involving cyclic AMP (cAMP), protein kinase A (PKA), protein kinase C (PKC), and calcium/calmodulin-dependent protein kinase II alpha (CAMKII)

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[8] Miller DC, Hafez KS, Stewart A, et al

[28] [29] There is also some evidence for loss of dendritic spines as a consequence of aging

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Multiple studies have indicated that certain TCM ingredients can influence the richness and species composition of the gut microbiome