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10.3389/fncel.2024.1305867 16

20 Specifically, TEPA inhibits the phosphorylation of STAT3 and EGFR, promotes the ubiquitin-mediated degradation of PD-L1, and significantly increases the infiltration of CD8 + T cells and natural killer cells, thereby enhancing antitumor immunity and slowing tumor growth

doi: 10.1016/j.intimp.2023.110018 54 EhrhardtCWolffTPleschkaSPlanzOBeermannWBodeJGet al

Together, the complementary knockdown and overexpression experiments delineate a causal role for mPFC-derived CCK in the modulation of affective behaviors under social stress, providing a compelling molecular entry point for the development of targeted treatments in anxiety-related pathologies

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But when the discs start deteriorating, pain sets in, signaled by neurons in the area