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doi: 10.1126/scitranslmed.aad3740 12 MetereAFrezzottiFGravesCEVergineMDe LucaAPietraforteDet al

PMID 5425759

Recent findings suggest that cancer cells preferentially sequester PLP, creating a nutrient-restricted, immunosuppressive niche that facilitates disease progression and immune evasion
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Mutations in SLC30A10 , which encodes ZNT10, also cause hypermanganesemia, with elevated Mn levels in the blood and brain

Sn phm nhp khu nn kh kim nh cht lng, d lm gi, gi thnh c th cao

From the perspective of the mitochondrial hypothesis of AD and the possibility of pharmacologically influencing mitochondrial dysfunction, the synaptic plasticity and metabolism of brain cells, CoQ 10 , and mitochondrial proteins and lipids interacting with it also appear to be potential targets for new AD drugs
