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Description
GLP-1 agonists influence the gut by slowing motility as part of their systemic metabolic and appetite-regulating function

GIP Receptor agonism attenuates GLP-1 receptor agonist-induced nausea and emesis in preclinical models

Inflammatory scores decreased markedly from day 14 to 28 in the treatment group, indicating a strong anti-inflammatory effect ( p 95% power ( = 0.05, n = 6 per group)

Methods: We examined all the trials registered on ClinicalTrials.gov from 2007 to 2021

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Peptides and proteins are large molecules with high potency and high specificity for their drug targets with a tendency for low off-target side-effects compared to small molecules
