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Innovations in the diagnosis, treatment, and management of disorders of gut-brain interaction (DGBI) Expert Rev Gastroenterol Hepatol

B12 is essential for healthy nerve cells and the production of myelin, the protective covering for nerves

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In addition to its anti-inflammatory properties, TRPA1 activation has been shown to protect against intestinal fibrosis, by the inhibition of TGF-1 and - SMA-dependent collagen production (Hiraishi et al., 2018)

The researchers did not observe evidence of inflammation, necrosis, or systemic toxicity, suggesting that nanoparticle delivery is safe for repeated dosing

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