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PM is classified by particle size, ranging from ultrafine (PM 0.1 ), fine (PM 2.5 ), to coarse (PM 10-2.5 )

For instance, pH-sensitive liposomes and hypoxia-activated prodrugs can selectively release ferroptosis inducers (e.g., erastin or RSL3) in the acidic or hypoxic TME, minimizing systemic exposure (282)

Harke S

It acts as a powerful antioxidant that protects cells from oxidative stress

The use of antioxidants including selenium, vitamin C, and vitamin E, has shown prospective effects when used to alleviate the symptoms of RA

The recently finished Phase 3 ABTECT programs (NCT05507203, NCT05507216) confirms the safety and efficacy of obefazimod, with a significant number of participants achieving clinical remission of UC, the results are waiting to be published, along with the completion of the long-term maintenance phase (NCT05535946) [126]