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Despite its intricate and context-specific function within the CNS, exhibiting both protective and detrimental impacts on neuronal and glial survival and function, LIF signaling is crucial for the maintenance of the nervous system (reviewed in: 34 )

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Most available data consists of observational reports from weight loss clinics where multiple interventions (caloric restriction, exercise programs, behavioral counseling) are implemented simultaneously, making it impossible to isolate the contribution of lipotropic injections

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