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A stepwise logistic regression was conducted to identify baseline PROMs associated with increasing EDSS scores

Then, the EEPT value is close to zero, and therefore, the EEPT/NEPT coefficient tends towards zero, which brings the solution of the equation closer to (or equal to) the value of 1

In vivo, both forms are expected to produce equivalent plasma concentration profiles at equimolar doses when formulated appropriately

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17 In FY23, there were 27 warning letters issued to firms based on 704(a)(4) requests