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Zhang Y., Zhang X., Yang X., et al., EGFRTKIs Induced DPP4 Drives Metabolic Reprogramming of Persister Cells in Lung Cancer, Advanced Science (Weinh) 12, no

No Phase 1 or Phase 2 trial has been conducted for PDA as a distinct compound

PMID: 34436223

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The "dose holiday" approach Some users and providers use brief dose reductions or pauses to restore receptor sensitivity