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Description
The degradation product of SAM, which is synthesized during the methylation reaction, namely SAH, is responsible for the inhibition of several methyltransferases

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& Dolores Dor Eccles Professor of Ophthalmology & Neuroscience, Wilmer Eye Institute, The Johns Hopkins School of Medicine involving oxidative stress in the retina provided impetus for exploring small molecule antioxidant therapies

Evaluation should be directed toward potential etiology

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