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In animal studies, oral lactobacillus reduced the BBB permeability, and consequently protected the postoperative cognitive functions of the aged and gut dysbiosis mice (Wen et al., 2020)

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Evidence from studies using Caco-2 epithelial cells shows that Gln deprivation significantly reduces the expression of TJs proteins, including ZO-1, occludin, and claudin-1, leading to increased epithelial permeability (Wang et al

Fabrication and Characterisation Studies of Cyclodextrin-Based Nanosponges for Sulfamethoxazole Delivery

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This results in a dramatic improvement in the productivity of the system