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Significant time-by-group interactions were observed for ARG ( p = 0.005), ORN ( p = 0.04), and ARG/ADMA ratio ( p = 0.007)

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ECM Remodeling: Collagen, Elastin, GAGs# In dermal fibroblasts, GHK-Cu upregulates type I and III collagen, elastin, decorin, and glycosaminoglycan synthesis while simultaneously activating matrix metalloproteinases (MMP-1, MMP-2) and their tissue inhibitors (TIMPs)

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Certain medications used to treat HTN, such as ACE inhibitors and angiotensin (Ag II) receptor AT1 antagonists, have shown antioxidant properties