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The additional adipose tissue in heavier individuals creates a larger target for the peptide but also means more tissue requires the signal to release stored lipids

Oral supplementation at high doses is generally effective even in the absence of intrinsic factor due to passive diffusion

8 mcg/day Children: 0.9 mcg/day (ages 1-3), 1.2 mcg/day (ages 4-8), and 1.8 mcg/day (ages 9-13) Teenagers: 2.4 mcg/day (ages 14-18) Supplementation needs If you are taking a liquid B12 supplement, the dosage might be higher than the RDA due to factors like absorption efficiency and individual health needs

Dry them completely

Careful handling of the mice will minimize these effects