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Another important fact for CRPeven when its precise form is not knownis that it can be rapidly and actively transported into the cell nuclei due to the presence of a nuclear localization sequence, and as it binds strongly to snRNPs both in vitro and in vivo, it is possibly involved in the clearance of these critical autoantigens

Alpha-lipoic acid as a biological antioxidant
10.1096/fj.08-128926 79 JardimF
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On the contrary, other studies with chronic supplementation protocols using lower or similar l-C doses (1 to 3 g/day) for periods between 4 and 24 weeks did not obtain improvements in this type of performance [15,30,34]

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