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Future directions Sixty years after antithyroid drugs introduction, these medications continue to be important in managing hyperthyroidism, but because of their potentially serious side effects such as hepatotoxicity, there is concern about their administration especially in pediatrics

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Studies reveal that the periodontal treatment result in improvement in salivary concentrations of glutathione and thiol levels in gingivitis and periodontitis subgroups, which was significant within groups, but not between groups.[50,102,107] Diab et al .,[111] reported improvement in salivary glutathione concentrations from 3.12 0.21 M/L to 3.6 0.22 M/L, collected in the patients with periodontal disease before and after treatment with mouthwash with extracts of Solanum melongena (egg-plant) peduncles against placebo during 3 months