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While much attention is given to B12 deficiency, known for causing fatigue, neurological changes, and anaemia, less is said about elevated B12 levels, which can be just as important to recognise 2

Greater investment in research and surveillance will help clinicians and public health professionals make evidence-based recommendations and better protect public health. Additionally, Piatkowski calls for longitudinal population-level data on peptides to model risk typologies and detect and report harm clusters

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Combination therapy is evaluated on a case-by-case basis, considering medical history, goals, and response to treatment

Approved peptide drugs (insulin, semaglutide, tirzepatide) sit in this latter category and should not be conflated with the grey-market research peptide space.