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In addition, due to such compensation, First Trust has an incentive to sell private investments issued by FTCM or offered through the First Trust Private Investment Platform, resulting in a material conflict of interest which should be considered when making a decision to invest in private funds offered by or through FTCM

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However, heterogeneity decreased importantly when excluding outliers (between-study variance=0.59, I 2 =73%), including only patients with moderate-to-severe AD (between-study variance=0.18, I2=44%), restricting to industry-sponsored trials (between-study variance=0.16, I 2 =43%) and using IPD only (between-study variance=0.12, I 2 =29%)

Rev Neurosci

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Devarajan, E