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Description

M.ReeseM

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Glossary Apo B apolipoprotein B ASCVD atherosclerotic cardiovascular disease CAD coronary artery disease CE cholesterol ester CETP cholesteryl ester transfer protein CHD coronary heart disease CVD cardiovascular disease FPLC fast protein liquid chromatography GGE gradient gel electrophoresis HDL high-density lipoprotein HPLC high-performance liquid chromatography HPSG heparan sulfate proteoglycan IDL intermediate density lipoprotein IMT intima media thickness LDL low-density lipoprotein LDL-C low-density lipoprotein cholesterol LDL-P low-density lipoprotein particle LDLR low-density lipoprotein receptor LOX1 lectin-like ox-LDL receptor LRP-1 low-density lipoprotein receptor-related protein 1 MTP microsomal triglyceride transfer protein NADPH nicotinamide adenine dinucleotide phosphate NMR nuclear magnetic resonance ox-LDL oxidized low-density lipoprotein PCSK9 proprotein convertase subtilsin/kexin type 9 PCSK9i proprotein convertase subtilsin/kexin type 9 inhibitor ROS reactive oxygen species sdLDL small dense low-density lipoprotein

Prakash, Y

We simulated proteins tethered to membranes using a worm-like chain model with a defined persistence length (L p ), which captures the resistance to bending, with L p =0 representing a freely-jointed chain (blue) and L p =infinity representing a rigid rod (grey) (Figs